SCHEMBL995546

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25562475	0.81	CCR1 (0.56)	CCR1CCR8TGFBR1CYP2A6METAP2
	SCHEMBL996802	0.80	NOS2 (0.41)	NOS3NOS2TDP1ALOX15CYP3A4
	SCHEMBL3723641	0.79	CCR1 (0.58)	CCR1CCR8NOS3NOS2TDP1
	SCHEMBL995619	0.79	CCR1 (0.44)	CCR1CCR8NOS3NOS2ALDH1A1
	SCHEMBL8090286	0.79	CCR1 (0.52)	CCR1CCR8TGFBR1CYP2A6METAP2
	SCHEMBL24224628	0.78	CCR1 (0.56)	CCR1CCR8TGFBR1CYP2A6METAP2
	SCHEMBL12270031	0.76	CCR1 (0.48)	CCR1CCR8CYP3A4TGFBR1ALDH1A1
	SCHEMBL7907148	0.76	CCR1 (0.58)	CCR1CCR8NOS3NOS2TGFBR1
	SCHEMBL462761	0.75	CCR1 (0.52)	CCR1CCR8NOS3NOS2TGFBR1
	SCHEMBL8101860	0.75	CCR1 (0.52)	CCR1CCR8NOS3NOS2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.