Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | CCR8 | P51685 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888380 | 0.86 | CCR1 (0.52) | CCR1CCR8TGFBR1GRM5HCRTR1 | |
| SCHEMBL2615815 | 0.83 | CCR1 (0.48) | CCR1CCR8TGFBR1GRM2CYP1A2 | |
| SCHEMBL6618989 | 0.83 | ASIC3 (0.42) | GRM2MAP3K5 | |
| SCHEMBL25562475 | 0.81 | CCR1 (0.56) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL8450245 | 0.79 | CCR1 (0.58) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL995546 | 0.79 | CCR1 (0.52) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL24224628 | 0.78 | CCR1 (0.56) | CCR1CCR8TGFBR1CYP2A6METAP2 | |
| SCHEMBL6622616 | 0.78 | MAP3K5 (0.38) | GRM2MAP3K5HSD17B10KDM1AHDAC1 | |
| SCHEMBL6622613 | 0.78 | MAP3K5 (0.38) | GRM2MAP3K5METAP2HSD17B10KDM1A | |
| SCHEMBL16277390 | 0.77 | SORT1 (0.55) | CCR1CCR8TGFBR1GRM5HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | PFIZER INC | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | NOS1, NOS3, NPBWR1 | CCR1 1520/4885CCR8 3120/4885TGFBR1 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.