SCHEMBL995563

SCHEMBL995563

CN(C)C(CCCNC(=N)N)C(=O)O.CN(C)[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.38
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
ALOX15 P16050 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 1/20 0.35
OTC P00480 1/20 0.33
FOLH1 Q04609 2/20 0.33
ALB P02768 1/20 0.32
DDAH1 O94760 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA4 P43681 1/20 0.32
ITGB3 P05106 1/20 0.32
ITGA2B P08514 1/20 0.32
NPY4R P50391 4/20 0.31
NPY1R P25929 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288819 1.00 NOS2 (0.38) NOS2NOS3NOS1ALOX15MEN1
SCHEMBL196827 1.00 NOS2 (0.38) NOS2NOS3NOS1ALOX15MEN1
SCHEMBL29770073 1.00 NOS2 (0.38) NOS2NOS3NOS1ALOX15MEN1
SCHEMBL160690 1.00 NOS2 (0.38) NOS2NOS3NOS1ALOX15MEN1
Hydrochloric Acid SCHEMBL12078158 0.98 NOS3 (0.37) NOS2NOS3NOS1ALOX15MEN1
Hydrochloric Acid SCHEMBL2595284 0.98 NOS3 (0.37) NOS2NOS3NOS1ALOX15MEN1
Hydrochloric Acid SCHEMBL12078437 0.98 NOS3 (0.37) NOS2NOS3NOS1ALOX15MEN1
Hydrochloric Acid SCHEMBL2595285 0.98 NOS3 (0.37) NOS2NOS3NOS1ALOX15MEN1
Dimethylamine SCHEMBL27821422 0.97 NOS3 (0.36) NOS2NOS3NOS1ALOX15MEN1
SCHEMBL1697811 0.95 ALOX15 (0.38) NOS2NOS3NOS1ALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2449488-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES Life Sciences AG (AT) 2012-05-09 EP disclosed
WO-2011000753-A1 METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES BIOCRATES LIFE SCIENCES AG (AT) 2011-01-06 WO disclosed