Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943566 | 0.78 | MEN1 (0.47) | GRM5SMN1; SMN2NPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL19552078 | 0.77 | MEN1 (0.46) | SMN1; SMN2NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7598688 | 0.77 | HPGD (0.52) | GRM5HPGDSMN1; SMN2LRRK2SLC6A2 | |
| Ammonia Solution, Strong SCHEMBL28789679 | 0.74 | HPGD (0.50) | GRM5HPGDSMN1; SMN2LRRK2SLC6A2 | |
| SCHEMBL1620588 | 0.73 | GAA (0.34) | MEN1KMT2A | |
| SCHEMBL28863144 | 0.71 | HPGD (0.44) | GRM5HPGDSMN1; SMN2LRRK2SLC6A2 | |
| SCHEMBL11465062 | 0.71 | ALDH1A1 (0.39) | SMN1; SMN2NPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL19552694 | 0.71 | L3MBTL1 (0.47) | GRM5HPGDSMN1; SMN2SLC6A2NPC1 | |
| SCHEMBL16579445 | 0.69 | HPGD (0.45) | GRM5HPGDSMN1; SMN2LRRK2MEN1 | |
| SCHEMBL2490706 | 0.69 | HPGD (0.45) | GRM5HPGDSMN1; SMN2LRRK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-9066945-B2 | Ectoparasiticidal active substance combinations | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| EP-2654425-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084852-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084852-A2 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | BAYER ANIMAL HEALTH GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179623-A1 | ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS | EPX, CAT, PIGO | GRM5 1651/4885HPGD 2000/4885SMN1; SMN2 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.