Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689823 | 0.87 | EPHX2 (0.56) | EPHX2MAPTKDM4ETRPV1KMT2A | |
| SCHEMBL27663883 | 0.87 | L3MBTL1 (0.50) | EPHX2MAPTKDM4EL3MBTL1KMT2A | |
| SCHEMBL4104600 | 0.86 | MAPT (0.56) | EPHX2MAPTKDM4EL3MBTL1TRPV1 | |
| Hydrochloric Acid SCHEMBL4482069 | 0.85 | MAPT (0.54) | EPHX2MAPTKDM4EL3MBTL1TRPV1 | |
| SCHEMBL11271295 | 0.84 | EPHX2 (0.71) | EPHX2MAPTKDM4ETRPV1KMT2A | |
| SCHEMBL11137428 | 0.84 | MAPT (0.71) | EPHX2MAPTKDM4EL3MBTL1TRPV1 | |
| SCHEMBL30096708 | 0.83 | EPHX2 (0.65) | EPHX2MAPTKDM4EL3MBTL1TRPV1 | |
| SCHEMBL23084203 | 0.81 | EPHX2 (0.62) | EPHX2MAPTKDM4EL3MBTL1TRPV1 | |
| SCHEMBL5035158 | 0.81 | MAPT (0.73) | EPHX2MAPTKDM4EL3MBTL1TRPV1 | |
| SCHEMBL169453 | 0.81 | EPHX2 (0.73) | EPHX2MAPTKDM4EL3MBTL1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085166-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |