Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.71 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955792 | 0.86 | ALDH1A1 (0.73) | ALDH1A1PDE7APDE7BHTTPKM | |
| SCHEMBL31519931 | 0.86 | GAA (0.59) | ALDH1A1PDE7APDE7BHTTPKM | |
| SCHEMBL6976082 | 0.86 | GAA (0.59) | ALDH1A1PDE7APDE7BHTTPKM | |
| SCHEMBL30103233 | 0.84 | PDE7A (1.00) | ALDH1A1PDE7APDE7BHTTLOXL3 | |
| SCHEMBL844588 | 0.84 | PDE7A (1.00) | ALDH1A1PDE7APDE7BHTTLOXL3 | |
| SCHEMBL5425840 | 0.82 | ALDH1A1 (0.59) | ALDH1A1PDE7APDE7BHTTPKM | |
| SCHEMBL14096394 | 0.75 | PDE7A (0.77) | ALDH1A1PDE7APDE7BHTTCA12 | |
| SCHEMBL18239987 | 0.75 | PDE7A (0.77) | ALDH1A1PDE7APDE7BHTTCA12 | |
| SCHEMBL6283505 | 0.75 | PDE7A (0.77) | ALDH1A1PDE7APDE7BHTTCA12 | |
| SCHEMBL31419817 | 0.75 | PDE7A (0.77) | ALDH1A1PDE7APDE7BHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212143-B2 | Small molecule inhibitors of protein kinases | LEVOLTA PHARMACEUTICALS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | LEVOLTA PHARMACEUTICALS, INC. | 2013-03-07 | — | — | US | disclosed |
| US-6897213-B1 | Heterocycles as cholecystokinin (CCK) ligands | WARNER-LAMBERT COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | SYK, BTK, LCK | ALDH1A1 4797/4885PDE7A 739/4885PDE7B 1319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.