Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 4/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16573945 | 0.81 | MAPT (0.45) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL9956115 | 0.81 | KDM4E (0.51) | MYCNR4A1ALDH1A1MAPTRAB9A | |
| SCHEMBL23981879 | 0.78 | MAPT (0.49) | MYCALDH1A1MAPTRAB9AKDM4E | |
| SCHEMBL4450463 | 0.75 | GAA (0.67) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL31316722 | 0.75 | F2 (0.51) | MYCNR4A1ALDH1A1MAPTKDM4E | |
| SCHEMBL10262760 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL25254882 | 0.74 | HTT (0.56) | ALDH1A1MAPTRAB9AKDM4EGAA | |
| SCHEMBL1339393 | 0.72 | ALDH1A1 (0.50) | MYCNR4A1ALDH1A1MAPTKDM4E | |
| SCHEMBL17256244 | 0.72 | MYC (0.51) | MYCNR4A1ALDH1A1MAPTTSHR | |
| SCHEMBL31525258 | 0.72 | RAB9A (0.43) | ALDH1A1MAPTRAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |
| CN-1391476-A | Vasopressin agonist formulation and process | AMERICAN CYANAMID CO (US) | 2003-01-15 | — | — | CN | disclosed |