Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.39 |
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262760 | 0.80 | ALDH1A1 (0.55) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL13078703 | 0.77 | MAPT (0.52) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL2615993 | 0.77 | MAPT (0.52) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL23751435 | 0.77 | TDO2 (0.53) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5543302 | 0.77 | RAB9A (0.52) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL16561619 | 0.77 | RAB9A (0.51) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL16911237 | 0.76 | RAB9A (0.65) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL9956153 | 0.75 | MYC (0.53) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL18713426 | 0.75 | RAB9A (0.50) | GAARAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL16910654 | 0.74 | MAPT (0.68) | GAARAB9AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-A1 | TOPICAL ANTIFUNGAL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2013-12-04 | — | — | EP | claimed |
| US-20130317074-A1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO., LTD. | 2013-11-28 | — | — | US | claimed |
| EP-4330233-A1 | PHENYL -O-QUINOLINE, QUINAZOLINE, THIENOPYRIDINE, THIENOPYRIMIDINE, PYRROLOPYRIDINE, PYRROLOPYRIMIDINE COMPOUNDS HAVING ANTICANCER ACTIVITY | Chengdu Anticancer Bioscience, Ltd. (CN) | 2024-03-06 | — | — | EP | disclosed |
| US-11466003-B2 | Nitrogenous heterocyclic aromatic compound, preparation method therefor, pharmaceutical composition thereof, and application thereof | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2022-10-11 | — | — | US | disclosed |
| US-20210300916-A1 | NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) | 2021-09-30 | — | — | US | disclosed |
| EP-3492461-A1 | NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | Shanghai Yingli Pharmaceutical Co. Ltd. (CN) | 2019-06-05 | — | — | EP | disclosed |
| US-10123978-B2 | Patch for treating dermatophytosis | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-11-13 | — | — | US | disclosed |
| EP-2881114-B1 | ANTI-TRICHOPHYTIC ADHESIVE PATCH | MEIJI SEIKA PHARMA CO LTD (JP) | 2018-09-05 | — | — | EP | disclosed |
| CN-108431002-A | Substituted pyrazolo [3, 4-b ] pyridine-6-carboxylic acids and uses thereof | 艾伯维公司 | 2018-08-21 | — | — | CN | disclosed |
| US-20180200199-A1 | PATCH FOR TREATING DERMATOPHYTOSIS | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2018-07-19 | — | — | US | disclosed |
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | disclosed |
| US-8889727-B2 | Topical antifungal agent | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-11-18 | — | — | US | disclosed |
| US-20140030209-A1 | TOPICAL LIQUID AGENT FOR THE TREATMENT OF DERMATOPHYTOSIS | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-01-30 | — | — | US | disclosed |
| EP-2669274-A1 | TOPICAL ANTIFUNGAL AGENT | Meiji Seika Pharma Co., Ltd. (JP) | 2013-12-04 | — | — | EP | disclosed |
| US-20130317074-A1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO., LTD. | 2013-11-28 | — | — | US | disclosed |
| US-20090156635-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS | GILLESPIE PAUL | 2009-06-18 | — | — | US | disclosed |
| US-7524870-B2 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activators | HOFFMANN-LA ROCHE INC. (US) | 2009-04-28 | — | — | US | disclosed |
| CN-101068803-A | Biaryloxymethylarene carboxylic acid compounds | HOFFMANN LA ROCHE (CH) | 2007-11-07 | — | — | CN | disclosed |
| US-20060122256-A1 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activators | GILLESPIE PAUL | 2006-06-08 | — | — | US | disclosed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180200199-A1 | PATCH FOR TREATING DERMATOPHYTOSIS | DPM1, KRT18, LCP1 | GAA 4547/4885RAB9A 3215/4885MAPT 1160/4885 |
| US-10123978-B2 | Patch for treating dermatophytosis | DPM1, KRT18, LCP1 | GAA 4547/4885RAB9A 3215/4885MAPT 1160/4885 |
| US-20090156635-A1 | BIARYLOXYMETHYLARENECARBOXYLIC ACIDS AS GLYCOGEN SYNTHASE ACTIVATORS | GYS2, GYS1, GSK3A | GAA 103/4885RAB9A 4301/4885MAPT 2951/4885 |
| US-20060122256-A1 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activators | GYS2, GYS1, GSK3A | GAA 103/4885RAB9A 4301/4885MAPT 2951/4885 |
| US-20130317074-A1 | TOPICAL ANTIFUNGAL AGENT | DPM1, ERG28, PIK3C3 | GAA 435/4885RAB9A 1239/4885MAPT 476/4885 |
| US-11466003-B2 | Nitrogenous heterocyclic aromatic compound, preparation method therefor, pharmaceutical composition thereof, and application thereof | NOTUM, ALKBH5, PAH | GAA 1363/4885RAB9A 3806/4885MAPT 3853/4885 |
| US-20140030209-A1 | TOPICAL LIQUID AGENT FOR THE TREATMENT OF DERMATOPHYTOSIS | POLR1C, CUTA, C1R | GAA 4050/4885RAB9A 1165/4885MAPT 3385/4885 |
| US-20210300916-A1 | NITROGENOUS HETEROCYCLIC AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION THEREOF | NOTUM, ALKBH5, PAH | GAA 1363/4885RAB9A 3806/4885MAPT 3853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.