SCHEMBL995624

SCHEMBL995624

CNC(Cc1ccc(OC)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.67
FPR2 P25090 1/20 0.58
KMT2A Q03164 1/20 0.58
CA2 P00918 1/20 0.55
PPARG P37231 2/20 0.53
PPARA Q07869 1/20 0.53
MMP2 P08253 2/20 0.51
MMP9 P14780 2/20 0.51
MMP1 P03956 1/20 0.51
MMP3 P08254 1/20 0.51
PTGDR Q13258 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16063575 1.00 LDHA (0.67) LDHAFPR2KMT2ACA2PPARG
SCHEMBL2029603 1.00 LDHA (0.67) LDHAFPR2KMT2ACA2PPARG
Hydrochloric Acid SCHEMBL7319628 0.98 LDHA (0.65) LDHAFPR2KMT2ACA2PPARG
Hydrochloric Acid SCHEMBL7319633 0.98 LDHA (0.65) LDHAFPR2KMT2ACA2PPARG
SCHEMBL14942967 0.87 LDHA (0.57) LDHAFPR2KMT2AMMP2MMP9
SCHEMBL8645164 0.87 LDHA (0.57) LDHAFPR2KMT2AMMP2MMP9
SCHEMBL19545998 0.87 LDHA (0.57) LDHAFPR2KMT2AMMP2MMP9
SCHEMBL7751730 0.87 LDHA (0.67) LDHAFPR2KMT2ACA2PPARG
SCHEMBL7751726 0.87 LDHA (0.67) LDHAFPR2KMT2ACA2PPARG
SCHEMBL13033619 0.87 LDHA (0.57) LDHAFPR2KMT2AMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4548814-A SOLVENT EXTRACTION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1985-10-22 US claimed
EP-0048149-B1 NOVEL ANTIBIOTICS, DERIVATIVES THEREOF, PROCESSES FOR THEIR EXTRACTION, AND COMPOSITIONS CONTAINING THEM University of Illinois Foundation (US) 1983-11-30 EP claimed
EP-0048149-A1 Novel antibiotics, derivatives thereof, processes for their extraction, and compositions containing them University of Illinois Foundation (US) 1982-03-24 EP claimed
US-12637494-B2 Method for producing peptide containing non-natural amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS MERCK SHARP & DOHME LLC (US) 2026-01-01 US disclosed
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-06 US disclosed
EP-4628592-A1 PEPTIDE PRODUCTION METHOD COMPRISING STEP FOR TRANSLATING AMINO ACID HAVING OXYGEN ATOM AT SPECIFIC POSITION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-10-08 EP disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12391971-B2 Method for synthesizing peptides in cell-free translation system CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-19 US disclosed
EP-4570371-A2 METHOD FOR PRODUCING CYCLIC ORGANIC COMPOUND Chugai Seiyaku Kabushiki Kaisha (JP) 2025-06-18 EP disclosed
CN-119080856-A Mutant tRNA for codon extension 中外制药株式会社 2024-12-06 CN disclosed
US-5137870-A Treating animal or human hosting leukemia THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1992-08-11 US disclosed
EP-0495013-A1 HEXAPEPTIDES WITH SULPHATE ESTER GROUPS. FISONS CORP (US) 1992-07-22 EP disclosed
WO-1991008225-A1 HEXAPEPTIDES WITH SULPHATE ESTER GROUPS FISONS CORPORATION (US) 1991-06-13 WO disclosed
US-4950649-A TREATING DNA AND RNA VIRUSES SUCH AS HERPES, VACCINIA, COXSACKIE AND EQUINE RHINO, AND ACCUTE LEUKEMIA UNIVERSITY OF ILLINOIS (US) 1990-08-21 US disclosed
US-4782135-A OLIGOPEPTIDE ANTIBIOTIC BOARD OF TRUSTEES, UNIVERSITY OF ILLINOIS (US) 1988-11-01 US disclosed
US-4548814-A SOLVENT EXTRACTION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1985-10-22 US disclosed
US-4493796-A ANTIBIOTICS BOARD OF TRUSTEES, UNIV. OF ILL. (US) 1985-01-15 US disclosed
EP-0048149-B1 NOVEL ANTIBIOTICS, DERIVATIVES THEREOF, PROCESSES FOR THEIR EXTRACTION, AND COMPOSITIONS CONTAINING THEM University of Illinois Foundation (US) 1983-11-30 EP disclosed
EP-0048149-A1 Novel antibiotics, derivatives thereof, processes for their extraction, and compositions containing them University of Illinois Foundation (US) 1982-03-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637494-B2 Method for producing peptide containing non-natural amino acid MRPL21, RPL21, RPL30 LDHA 1374/4885FPR2 1653/4885KMT2A 2790/4885
US-12391971-B2 Method for synthesizing peptides in cell-free translation system AARS1, NSUN3, RNGTT LDHA 2627/4885FPR2 883/4885KMT2A 1543/4885
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS KRAS, NRAS, HRAS LDHA 4318/4885FPR2 1120/4885KMT2A 2905/4885
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM AARS1, NSUN3, RNGTT LDHA 2627/4885FPR2 883/4885KMT2A 1543/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R LDHA 4349/4885FPR2 190/4885KMT2A 4608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.