Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090742 | 0.86 | CYP19A1 (0.48) | MEN1MAPTKMT2AGRK6ALDH1A1 | |
| SCHEMBL6351188 | 0.82 | AHR (0.43) | AHRMAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL1317350 | 0.81 | AHR (0.56) | AHRMAPTKMT2APDK2ALDH1A1 | |
| SCHEMBL11094233 | 0.81 | AHR (0.59) | AHRPDK2SMYD3GRM5 | |
| SCHEMBL7211895 | 0.80 | BRD4 (0.53) | AHRMEN1MAPTKMT2APDK2 | |
| SCHEMBL10560457 | 0.78 | ALDH1A1 (0.48) | AHRSMN1; SMN2PDK2ALDH1A1SMYD3 | |
| SCHEMBL12462776 | 0.76 | AHR (0.58) | AHRMEN1MAPTKMT2APDK2 | |
| SCHEMBL11091415 | 0.75 | AHR (0.49) | AHRMAPTPDK2ALDH1A1MAPK1 | |
| SCHEMBL28870646 | 0.74 | DRD2 (0.56) | MEN1MAPTKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL9375531 | 0.74 | AHR (0.51) | AHRPDK2SMYD3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655361-A2 | METHOD FOR PRODUCING TRIAZINYL-SUBSTITUTED OXINDOLES | Bayer Intellectual Property GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084855-A2 | METHOD FOR PRODUCING TRIAZINYL-SUBSTITUTED OXINDOLES | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | WO | disclosed |
| US-4110466-A | FUNGICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-08-29 | — | — | US | disclosed |