Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957466 | 0.86 | RORC (0.35) | KCNH2CHIT1CHIAS1PR1GRK5 | |
| SCHEMBL3577580 | 0.83 | LMNA (0.38) | KCNH2CHIT1CHIAS1PR1GRK5 | |
| SCHEMBL3576111 | 0.77 | LMNA (0.41) | KCNH2CHIT1CHIAS1PR1GRK5 | |
| SCHEMBL9958958 | 0.74 | SLC2A1 (0.39) | S1PR1GRK5CDK8S1PR5SLC2A1 | |
| SCHEMBL9957400 | 0.73 | RCE1 (0.39) | S1PR1GRK5CDK8S1PR5SLC2A1 | |
| SCHEMBL3576810 | 0.73 | LMNA (0.42) | S1PR1GRK5CDK8S1PR5SLC2A1 | |
| SCHEMBL3577493 | 0.72 | LMNA (0.40) | S1PR1GRK5CDK8S1PR5LMNA | |
| SCHEMBL12521079 | 0.72 | LMNA (0.44) | S1PR1GRK5CDK8S1PR5SLC2A1 | |
| SCHEMBL3574585 | 0.72 | LMNA (0.42) | KCNH2CHIT1CHIAS1PR1GRK5 | |
| SCHEMBL3576623 | 0.72 | LMNA (0.41) | S1PR1GRK5CDK8S1PR5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |