Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957283 | 1.00 | GPR119 (0.50) | GPR119HCRTR1HCRTR2RETHCAR2 | |
| SCHEMBL1586058 | 0.91 | HCRTR1 (0.51) | HCRTR1HCRTR2HCAR2 | |
| SCHEMBL9957068 | 0.88 | RET (0.46) | GPR119HCRTR1HCRTR2RETDPP4 | |
| SCHEMBL9957065 | 0.88 | RET (0.46) | GPR119HCRTR1HCRTR2RETDPP4 | |
| SCHEMBL9957542 | 0.84 | HCRTR1 (0.50) | HCRTR1HCRTR2HCAR2DPP4DPP8 | |
| SCHEMBL3486737 | 0.83 | GPR119 (0.69) | GPR119CKS1BSKP1SKP2 | |
| SCHEMBL9957734 | 0.83 | RET (0.42) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL9957737 | 0.83 | RET (0.42) | GPR119RETCKS1BSKP1SKP2 | |
| SCHEMBL6908647 | 0.80 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL1673184 | 0.80 | HCRTR1 (0.63) | GPR119HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |