Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583039 | 0.92 | CNR1 (0.43) | C5AR1CNR1RCE1MCL1UTS2R | |
| SCHEMBL3578978 | 0.89 | CNR1 (0.43) | C5AR1CNR1RCE1CYP1A2CYP2D6 | |
| SCHEMBL27730382 | 0.89 | C5AR1 (0.39) | C5AR1CNR1RCE1GAAMLYCD | |
| SCHEMBL3577159 | 0.84 | C5AR1 (0.42) | C5AR1GAAALDH1A1UTS2RLMNA | |
| SCHEMBL3579938 | 0.83 | MAPT (0.42) | CNR1RCE1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL3580876 | 0.83 | LPAR1 (0.36) | C5AR1CNR1RCE1GAAALDH1A1 | |
| SCHEMBL3589192 | 0.83 | PPARA (0.39) | C5AR1RCE1ALDH1A1SMN1; SMN2LPAR1 | |
| SCHEMBL3583296 | 0.81 | LPAR1 (0.52) | C5AR1RCE1LPAR1LPAR5 | |
| SCHEMBL27730385 | 0.80 | LMNA (0.43) | C5AR1CNR1GAAALDH1A1L3MBTL1 | |
| SCHEMBL3581360 | 0.79 | MCL1 (0.40) | CNR1GAAMCL1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |