Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493062 | 0.77 | EGLN1 (0.56) | L3MBTL1EGLN1 | |
| SCHEMBL15419070 | 0.67 | L3MBTL1 (0.45) | L3MBTL1EGLN1SMN1; SMN2 | |
| SCHEMBL15418951 | 0.67 | EGLN1 (0.64) | L3MBTL1EGLN1 | |
| SCHEMBL4208230 | 0.65 | EGLN1 (0.38) | L3MBTL1EGLN1ALDH1A1 | |
| SCHEMBL15419051 | 0.64 | L3MBTL1 (0.42) | L3MBTL1EGLN1SMN1; SMN2 | |
| SCHEMBL15419072 | 0.63 | L3MBTL1 (0.44) | L3MBTL1EGLN1 | |
| SCHEMBL27734743 | 0.60 | TAS1R3 (0.66) | CA2PYGLCYP2C9SMN1; SMN2 | |
| SCHEMBL27734667 | 0.60 | TAS1R3 (0.66) | CA2PYGLCYP2C9SMN1; SMN2 | |
| SCHEMBL2496235 | 0.60 | EGLN1 (0.41) | L3MBTL1EGLN1PYGLALDH1A1SMN1; SMN2 | |
| SCHEMBL2495407 | 0.59 | EGLN1 (0.53) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150251-B9 | THIENOPYRIDINE AND THIAZOLOPYRIDINE DERIVATIVES THAT INHIBIT PROLYL HYDROXYLASE ACTIVITY | AMGEN INC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2150251-B1 | THIENOPYRIDINE AND THIAZOLOPYRIDINE DERIVATIVES THAT INHIBIT PROLYL HYDROXYLASE ACTIVITY | AMGEN INC (US) | 2012-06-27 | — | — | EP | disclosed |