Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 18/20 | 0.48 |
| ▸ | BRAF | P15056 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958072 | 0.94 | MET (0.58) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958154 | 0.93 | MET (0.52) | METPDGFRBPDGFRAKDR | |
| SCHEMBL13861594 | 0.90 | MET (0.52) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958865 | 0.87 | MET (0.53) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958601 | 0.87 | MET (0.48) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL4326264 | 0.85 | MET (0.53) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL13861601 | 0.85 | MET (0.60) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL4343909 | 0.84 | MET (0.56) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958796 | 0.84 | MET (0.54) | METKDR | |
| SCHEMBL13861600 | 0.84 | MET (0.56) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |