SCHEMBL9959545

SCHEMBL9959545

CCOc1cc(CO)ccc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.48
S1PR1 P21453 5/20 0.46
S1PR3 Q99500 4/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 3/20 0.41
LMNA P02545 3/20 0.41
POLB P06746 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
CYP2D6 P10635 1/20 0.41
CYP3A4 P08684 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
TSHR P16473 1/20 0.38
DRD1 P21728 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9959203 0.88 DRD2 (0.47) DRD2S1PR1S1PR3ALDH1A1MAPK1
SCHEMBL3119147 0.85 DRD2 (0.56) DRD2HTTALDH1A1LMNAPOLB
SCHEMBL499011 0.82 DRD2 (0.50) DRD2S1PR1HTTALDH1A1LMNA
SCHEMBL3113521 0.81 DRD2 (0.41) DRD2S1PR1S1PR3HTTALDH1A1
SCHEMBL9452824 0.81 DRD2 (0.41) DRD2HTTPOLBNPC1RAB9A
SCHEMBL697888 0.81 HTT (0.61) S1PR1S1PR3HTTALDH1A1MAPK1
SCHEMBL26491007 0.80 DRD2 (0.43) DRD2S1PR1S1PR3POLBNPC1
SCHEMBL9128232 0.79 NPC1 (0.43) DRD2HTTPOLBSMN1; SMN2NPC1
SCHEMBL7262108 0.79 DRD2 (0.39) DRD2S1PR1S1PR3ALDH1A1MAPK1
SCHEMBL9137815 0.78 DRD2 (0.40) DRD2S1PR1S1PR3POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655307-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS Givaudan SA (CH) 2013-10-30 EP disclosed
WO-2012085287-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2012-06-28 WO disclosed