Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499011 | 0.94 | DRD2 (0.50) | DRD2POLBNPC1RAB9AACHE | |
| SCHEMBL9959545 | 0.85 | DRD2 (0.48) | DRD2POLBNPC1RAB9AHTT | |
| SCHEMBL6663695 | 0.84 | DRD2 (0.53) | DRD2POLBCA2HTTKDM4E | |
| SCHEMBL3113521 | 0.84 | DRD2 (0.41) | DRD2POLBNPC1RAB9AHTT | |
| SCHEMBL7484802 | 0.83 | DRD2 (0.61) | DRD2NPC1HTTGAAALDH1A1 | |
| SCHEMBL29565908 | 0.83 | DRD2 (0.55) | DRD2POLBCA2CA1CA9 | |
| SCHEMBL9452824 | 0.83 | DRD2 (0.41) | DRD2POLBNPC1RAB9AACHE | |
| SCHEMBL1635299 | 0.83 | DRD2 (0.51) | DRD2POLBCA2CA1CA9 | |
| SCHEMBL26491007 | 0.83 | DRD2 (0.43) | DRD2POLBNPC1RAB9AACHE | |
| SCHEMBL21359165 | 0.82 | DRD2 (0.64) | DRD2NPC1CA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| US-20100256413-A1 | METHOD FOR THE CHEMICAL SYNTHESIS OF CAPSINOIDS | UNIVERSIDAD DE CÁDIZ (ES) | 2010-10-07 | — | — | US | disclosed |
| EP-2149548-A1 | METHOD FOR THE CHEMICAL SYNTHESIS OF CAPSINOIDS | Universidad De Cádiz (ES) | 2010-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256413-A1 | METHOD FOR THE CHEMICAL SYNTHESIS OF CAPSINOIDS | CES2, ACACB, TES | DRD2 908/4885POLB 2651/4885NPC1 980/4885 |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | PPIA, S100A4, S100A6 | DRD2 4707/4885POLB 2430/4885NPC1 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.