SCHEMBL9959554

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL167348	0.86	PDE10A (0.40)	PDE2APDE10AAGPAT2CNR2PIK3CA
	SCHEMBL15426448	0.86	PIK3CA (0.41)	AGPAT2CNR2PIK3CAPIK3CBPIK3CG
	SCHEMBL15426340	0.85	NLRP3 (0.44)	PDE10AAGPAT2KDM4ECYP1A2ALDH1A1
	SCHEMBL29431625	0.84	HTR2B (0.38)	PDE2APDE10AAGPAT2CNR2PIK3CA
	SCHEMBL14684635	0.84	HTR2B (0.38)	PDE2APDE10AAGPAT2CNR2PIK3CA
	SCHEMBL18819829	0.83	CNR2 (0.40)	PDE2APDE10AAGPAT2CNR2KDM4E
	SCHEMBL15412786	0.83	POLB (0.43)	PDE2APDE10AKDM4EALDH1A1HSD11B1
	SCHEMBL15427221	0.82	AGPAT2 (0.37)	PDE2APDE10AAGPAT2CNR2PIK3CA
	SCHEMBL9958662	0.82	HSD11B1 (0.36)	PDE2APDE10AAGPAT2HSD11B1GRM2
	SCHEMBL9958651	0.82	HSD11B1 (0.33)	PDE2APDE10AHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.