Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.38 |
| ▸ | CPB1 | P15086 | 4/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8843361 | 0.99 | CPB2 (0.37) | CPB2CPB1CPA1FPR1 | |
| Hydrochloric Acid SCHEMBL8844341 | 0.79 | LMNA (0.43) | CPB2DCAF1 | |
| Hydrochloric Acid SCHEMBL8340839 | 0.77 | SYK (0.37) | CPB2HTT | |
| Hydrochloric Acid SCHEMBL8844102 | 0.71 | MEN1 (0.45) | TSHRGAA | |
| SCHEMBL9953903 | 0.70 | CPB2 (0.43) | CPB2CPB1CPA1FPR1CYP2C9 | |
| Hydrochloric Acid SCHEMBL8843356 | 0.69 | CPB2 (0.44) | CPB2CPB1CYP2C9TSHRCYP2C19 | |
| SCHEMBL3206859 | 0.66 | CPB2 (0.46) | CPB2CPB1CPA1FPR1CYP2C9 | |
| SCHEMBL5869564 | 0.66 | CPB2 (0.46) | CPB2CPB1CPA1 | |
| SCHEMBL19674649 | 0.65 | — | — | |
| SCHEMBL12669824 | 0.64 | CPB2 (0.38) | CPB2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655330-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | Purdue Pharma LP (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085650-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |