Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 5/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086333 | 0.86 | CCR2 (0.55) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL6084959 | 0.83 | MEN1 (0.49) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL9959670 | 0.81 | HDAC1 (0.45) | CCR2TBXA2RRAB9AGALR3NR2F2 | |
| SCHEMBL9958735 | 0.81 | KDM4E (0.50) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL9958540 | 0.81 | BRD4 (0.48) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL9959205 | 0.81 | MEN1 (0.56) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL6823866 | 0.80 | CCR2 (0.52) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL6086266 | 0.78 | HDAC1 (0.62) | CCR2RAB9AGALR3NR2F2HDAC1 | |
| SCHEMBL6085520 | 0.78 | CCR2 (0.56) | CCR2MEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9958509 | 0.78 | CCR2 (0.44) | CCR2RAB9AGALR3NR2F2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088431-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |