Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242573 | 0.94 | FAAH (0.60) | FAAHSCN10ATP53MAPTRXFP1 | |
| SCHEMBL9960022 | 0.92 | FAAH (0.58) | FAAHSCN10APLA2G2AKDRGRM4 | |
| SCHEMBL9960013 | 0.92 | FAAH (0.60) | FAAHSCN10ATP53MAPTRXFP1 | |
| SCHEMBL10242361 | 0.92 | FAAH (0.62) | FAAHSCN10AMAPTCNR1PLA2G2A | |
| SCHEMBL9960948 | 0.91 | FAAH (0.60) | FAAHSCN10ATP53MAPTRXFP1 | |
| SCHEMBL9956255 | 0.90 | FAAH (0.75) | FAAHSCN10AMAPTPLA2G2AMAPK3 | |
| SCHEMBL9959182 | 0.89 | FAAH (0.71) | FAAHSCN10AMAPTCNR1PLA2G2A | |
| SCHEMBL9959139 | 0.88 | FAAH (0.65) | FAAHMAPTPLA2G2A | |
| SCHEMBL9960034 | 0.88 | FAAH (0.62) | FAAHSCN10AMAPTPLA2G2A | |
| SCHEMBL9953124 | 0.86 | FAAH (0.80) | FAAHSCN10AMAPTCNR1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088431-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088431-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |