Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.45 |
| ▸ | SPR | P35270 | 5/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960638 | 1.00 | GPR119 (0.46) | GPR119HCRTR1HCRTR2SPRUSP30 | |
| SCHEMBL9955954 | 0.88 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL9954840 | 0.83 | HCRTR1 (0.53) | GPR119HCRTR1HCRTR2SPRUSP30 | |
| SCHEMBL9960673 | 0.83 | HCRTR1 (0.53) | GPR119HCRTR1HCRTR2SPRUSP30 | |
| SCHEMBL9960725 | 0.81 | HCRTR1 (0.49) | HCRTR1HCRTR2SPR | |
| SCHEMBL9956100 | 0.81 | HCRTR1 (0.49) | HCRTR1HCRTR2SPR | |
| SCHEMBL9959143 | 0.80 | SPR (0.46) | GPR119HCRTR1HCRTR2SPRUSP30 | |
| SCHEMBL9957879 | 0.78 | GPR119 (0.50) | GPR119HCRTR1HCRTR2SPRUSP30 | |
| Hydrochloric Acid SCHEMBL9960672 | 0.77 | HCRTR1 (0.46) | HCRTR1HCRTR2SPR | |
| Hydrochloric Acid SCHEMBL9960679 | 0.77 | HCRTR1 (0.46) | HCRTR1HCRTR2SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |