Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.53 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 2/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954840 | 1.00 | HCRTR1 (0.53) | HCRTR1HCRTR2GPR119SPRCYP46A1 | |
| SCHEMBL9957879 | 0.93 | GPR119 (0.50) | HCRTR1HCRTR2GPR119SPRUSP30 | |
| SCHEMBL9954691 | 0.87 | HCRTR1 (0.58) | HCRTR1HCRTR2CYP46A1 | |
| SCHEMBL9956117 | 0.84 | HCRTR1 (0.53) | HCRTR1HCRTR2CYP46A1 | |
| SCHEMBL9960641 | 0.83 | GPR119 (0.46) | HCRTR1HCRTR2GPR119SPRUSP30 | |
| SCHEMBL9960638 | 0.83 | GPR119 (0.46) | HCRTR1HCRTR2GPR119SPRUSP30 | |
| SCHEMBL9956489 | 0.80 | HCRTR1 (0.64) | HCRTR1HCRTR2SPR | |
| SCHEMBL9954161 | 0.79 | SPR (0.51) | HCRTR1HCRTR2SPR | |
| SCHEMBL9954160 | 0.79 | SPR (0.51) | HCRTR1HCRTR2SPR | |
| Hydrochloric Acid SCHEMBL9955299 | 0.77 | HCRTR1 (0.51) | HCRTR1HCRTR2CYP46A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |