Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.71 |
| ▸ | THPO | P40225 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | GNPAT | O15228 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13295204 | 1.00 | KDM4E (0.71) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL377413 | 0.86 | KDM4E (0.65) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL435838 | 0.86 | KDM4E (0.65) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL12807977 | 0.86 | KDM4E (0.65) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5291 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL5292 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3923962 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL149212 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL3688241 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 | |
| Acetylcysteine SCHEMBL4437350 | 0.83 | MAPT (1.00) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306550-A1 | HYDROGELS FOR CELL THERAPY | Adocia (FR) | 2024-01-17 | — | — | EP | disclosed |
| US-20230193244-A1 | Methods For Split-Protein Template Assembly By Proximity-Enhanced Reactivity | TRIBIOTICA LLC | 2023-06-22 | — | — | US | disclosed |
| WO-2023065551-A1 | AGGREGATE FORMED BY MEANS OF ASSEMBLING CHALCOGEN HETEROCYCLIC COMPOUND AND INSULIN, AND PREPARATION METHOD THEREFOR, AND INSULIN ORAL PREPARATION | 福州大学 | 2023-04-27 | — | — | WO | disclosed |
| WO-2023065550-A1 | POLYDISULFIDE POLYPEPTIDE NANOPARTICLE, PREPARATION METHOD THEREFOR, AND POLYPEPTIDE DRUG ORAL PREPARATION | 福州大学 | 2023-04-27 | — | — | WO | disclosed |
| WO-2022084738-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF OCULAR DISORDERS | Azura Ophthalmics Ltd. (IL) | 2022-04-28 | — | — | WO | disclosed |
| WO-2021045632-A1 | CANCER VACCINE | VICTORIA LINK LTD (NZ) | 2021-03-11 | — | — | WO | disclosed |
| EP-3201168-B1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF MULTIPLE SCLEROSIS | CELLIX BIO PRIVATE LTD (IN) | 2020-03-18 | — | — | EP | disclosed |
| EP-2928902-B1 | CONJUGATE COMPOUNDS | VICTORIA LINK LTD (NZ) | 2019-07-17 | — | — | EP | disclosed |
| WO-2019058289-A1 | MAIT CELL AGONISTS | VICTORIA LINK LIMITED (NZ) | 2019-03-28 | — | — | WO | disclosed |
| WO-2019005966-A1 | DENDRIMER DRUG CONJUGATES FOR SUSTAINED INTRA-ARTICULAR DELIVERY | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-01-03 | — | — | WO | disclosed |
| US-7803777-B2 | Branched water-soluble polymers and their conjugates | BIOGENERIX AG (DE) | 2010-09-28 | — | — | US | disclosed |
| US-7718598-B1 | Auxiliary for amide bond formation | THE UNIVERSITY OF QUEENSLAND (AU) | 2010-05-18 | — | — | US | disclosed |
| US-7645454-B2 | Antibody or antibody fragment which binds specifically to a normal or transformed PSA glycan or glycopeptide | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-01-12 | — | — | US | disclosed |
| US-7635750-B2 | Reacting a peptide acyl donor comprising a peptidic backbone made up of two or more amino acids with a peptide amine acceptor under reducing reaction conditions employing an excess of a reducing agent; | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2009-12-22 | — | — | US | disclosed |
| WO-2009143299-A1 | HEPATOPROTECTANT ACETAMINOPHEN MUTUAL PRODRUGS | NEUROGESX, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009138437-A1 | SALICYLATE CONJUGATES USEFUL FOR TREATING METABOLIC DISORDERS | GENMEDICA THERAPEUTICS SL (ES) | 2009-11-19 | — | — | WO | disclosed |
| US-20070173636-A1 | Method for preparing polyfunctionalized peptides and/or proteins via native chemical ligation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-26 | — | — | US | disclosed |
| US-7186708-B2 | Steroidal compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | disclosed |
| US-20070032405-A1 | Branched water-soluble polymers and their conjugates | NEOSE TECHNOLOGIES, INC. (US) | 2007-02-08 | — | — | US | disclosed |
| US-20070020224-A1 | Protein-proteophore complexes | ASCENDIS PHARMA GMBH (DE) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020224-A1 | Protein-proteophore complexes | PSMG3, PSME1, PSMD11 | KDM4E 3799/4885MAPT 1228/4885THRB 3691/4885 |
| US-20070032405-A1 | Branched water-soluble polymers and their conjugates | SLC7A5, SLC43A1, SLC7A1 | KDM4E 4463/4885MAPT 1895/4885THRB 3685/4885 |
| US-20070173636-A1 | Method for preparing polyfunctionalized peptides and/or proteins via native chemical ligation | TXNL1, NGLY1, RXFP1 | KDM4E 2759/4885MAPT 4567/4885THRB 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.