Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.51 |
| ▸ | HIF1AN | Q9NWT6 | 5/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996372 | 1.00 | ACHE (0.52) | ACHEMAOBTNFRSF1AHIF1ANABCG2 | |
| SCHEMBL995795 | 0.99 | TNFRSF1A (0.52) | ACHEMAOBTNFRSF1AHIF1ANABCG2 | |
| SCHEMBL995798 | 0.99 | TNFRSF1A (0.52) | ACHEMAOBTNFRSF1AHIF1ANABCG2 | |
| SCHEMBL996811 | 0.92 | KDM4E (0.56) | TNFRSF1AHIF1ANABCG2KDM4EALDH1A1 | |
| SCHEMBL996808 | 0.92 | KDM4E (0.56) | TNFRSF1AHIF1ANABCG2KDM4EALDH1A1 | |
| SCHEMBL998727 | 0.88 | MAPT (0.59) | MAOBHIF1ANABCG2KDM4EALDH1A1 | |
| SCHEMBL998730 | 0.88 | MAPT (0.59) | MAOBHIF1ANABCG2KDM4EALDH1A1 | |
| SCHEMBL997110 | 0.87 | MAPT (0.60) | ACHEMAOBHIF1ANABCG2BCHE | |
| SCHEMBL997108 | 0.87 | MAPT (0.60) | ACHEMAOBHIF1ANABCG2BCHE | |
| SCHEMBL998223 | 0.86 | HIF1AN (0.54) | ACHEMAOBHIF1ANABCG2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | claimed |
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |