SCHEMBL9964649

SCHEMBL9964649

CCC(C)OC(=O)OCC(C)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.43
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
MAPK1 P28482 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2990189 0.85 TSHR (0.42) MAPTTSHRHSD17B10TDP1MAPK1
SCHEMBL1218297 0.85 TSHR (0.42) MAPTTSHRHSD17B10TDP1MAPK1
SCHEMBL31731078 0.85 MAPT (0.36) MAPTTSHRTDP1ALDH1A1SOAT1
SCHEMBL9964654 0.85 MAPT (0.40) MAPTTSHRHSD17B10TDP1MAPK1
SCHEMBL4439992 0.85 TSHR (0.42) MAPTTSHRHSD17B10TDP1MAPK1
SCHEMBL15441005 0.83 MAPT (0.39) MAPTTSHRHSD17B10TDP1MAPK1
SCHEMBL12262559 0.83 MAPT (0.39) MAPTTSHRHSD17B10TDP1MAPK1
SCHEMBL2991296 0.83 MAPT (0.43) MAPTALDH1A1SOAT1
SCHEMBL4438761 0.83 MAPT (0.43) MAPTALDH1A1SOAT1
SCHEMBL2988909 0.83 MAPT (0.43) MAPTALDH1A1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11753503-B2 Supported onium salts as initiators for the synthesis of polycarbonates by copolymerization of CO2 with epoxides KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2023-09-12 US disclosed
US-9771453-B2 Process of producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same as catalyst SK INNOVATION CO., LTD. (KR) 2017-09-26 US disclosed
US-9738784-B2 Polymer blends NOVOMER, INC. (US) 2017-08-22 US disclosed
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NOVOMER, INC. (US) 2017-04-20 US disclosed
US-9403861-B2 Salen complexes with dianionic counterions NOVOMER, INC. (US) 2016-08-02 US disclosed
US-20160075824-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SK INNOVATION CO LTD (KR) 2016-03-17 US disclosed
US-9217057-B2 Coordination complexes for producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same as catalyst SK INNOVATION CO., LTD. (KR) 2015-12-22 US disclosed
US-20140336354-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2014-11-13 US disclosed
US-20140221605-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SK INNOVATION CO., LTD. (KR) 2014-08-07 US disclosed
US-8791274-B2 Coordination complexes and process of producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same as catalyst SK INNOVATION CO., LTD. (KR) 2014-07-29 US disclosed
US-8748555-B2 Structurally precise poly(propylene carbonate) compositions NOVOMER, INC. (US) 2014-06-10 US disclosed
US-8642721-B2 Coordination complexes and process of producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same catalyst SK INNOVATION CO., LTD. (KR) 2014-02-04 US disclosed
US-20130209775-A1 POLYMER BLENDS NOVOMER, INC. (US) 2013-08-15 US disclosed
US-8507733-B2 Coordination complexes and process of producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same as catalyst SK INNOVATION CO., LTD. (KR) 2013-08-13 US disclosed
US-20120178899-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME CATALYST SK INNOVATION CO., LTD. (KR) 2012-07-12 US disclosed
US-20120165575-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SK ENERGY CO., LTD. (KR) 2012-06-28 US disclosed
US-20120165549-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SK ENERGY CO., LTD. (KR) 2012-06-28 US disclosed
US-20120156410-A1 STRUCTURALLY PRECISE POLY(PROPYLENE CARBONATE) COMPOSITIONS NOVOMER, INC. (US) 2012-06-21 US disclosed
US-20100029896-A1 Novel Coordination complexes and process of producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same as catalyst SK INNOVATION CO., LTD. (KR) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170107241-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NCLN, POLN, NCL MAPT 1373/4885TSHR 4704/4885HSD17B10 2041/4885
US-20120165575-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SCO2, EMC2, CA2 MAPT 4211/4885TSHR 4771/4885HSD17B10 1300/4885
US-20140336354-A1 SALEN COMPLEXES WITH DIANIONIC COUNTERIONS NCLN, POLN, NCL MAPT 1373/4885TSHR 4704/4885HSD17B10 2041/4885
US-20120178899-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME CATALYST EMC2, SCO2, ELP1 MAPT 4224/4885TSHR 4773/4885HSD17B10 1220/4885
US-20160075824-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SCO2, EMC2, CA2 MAPT 4211/4885TSHR 4771/4885HSD17B10 1300/4885
US-20100029896-A1 Novel Coordination complexes and process of producing polycarbonate by copolymerization of carbon dioxide and epoxide using the same as catalyst SCO2, EMC2, CA2 MAPT 4211/4885TSHR 4771/4885HSD17B10 1300/4885
US-20120165549-A1 NOVEL COORDINATION COMPLEXES AND PROCESS OF PRODUCING POLYCARBONATE BY COPOLYMERIZATION OF CARBON DIOXIDE AND EPOXIDE USING THE SAME AS CATALYST SCO2, EMC2, CA2 MAPT 4211/4885TSHR 4771/4885HSD17B10 1300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.