Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 16/20 | 0.43 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073333 | 0.84 | DPP4 (0.49) | DPP4DPP8DPP9XIAPMLX | |
| SCHEMBL18754863 | 0.84 | BIRC2 (0.45) | DPP4BIRC2XIAP | |
| SCHEMBL10078889 | 0.84 | BIRC2 (0.45) | DPP4BIRC2XIAP | |
| SCHEMBL3796192 | 0.84 | ACE (0.50) | DPP4DPP8DPP9BIRC2XIAP | |
| SCHEMBL18474879 | 0.82 | DPP4 (0.68) | DPP4DPP8DPP9 | |
| SCHEMBL16137996 | 0.82 | BIRC2 (0.54) | DPP4DPP8DPP9BIRC2XIAP | |
| SCHEMBL12675437 | 0.82 | XIAP (0.42) | DPP4DPP8DPP9BIRC2XIAP | |
| SCHEMBL13050530 | 0.82 | FAP (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL12747467 | 0.82 | FAP (0.45) | DPP4DPP8DPP9 | |
| SCHEMBL13673006 | 0.82 | BIRC2 (0.49) | DPP4DPP8DPP9BIRC2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080271-A1 | DIMERIC IAP INHIBITORS | NOVARTIS AG (CH) | 2012-06-21 | — | — | WO | disclosed |