Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966057 | 1.00 | KMT2A (0.53) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL1593734 | 0.88 | ALDH1A1 (0.53) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL1593723 | 0.88 | ALDH1A1 (0.53) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL1594713 | 0.88 | ALDH1A1 (0.53) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL9966093 | 0.81 | KMT2A (0.42) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL14412293 | 0.77 | CHRNB2 (0.43) | KMT2AMEN1HTTKDM4ERAB9A | |
| SCHEMBL14412549 | 0.76 | ALDH1A1 (0.47) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL14412372 | 0.75 | ALDH1A1 (0.42) | KDM4ERAB9AALDH1A1 | |
| SCHEMBL9966059 | 0.74 | NPC1 (0.48) | KMT2AMEN1HPGDTSHRHSD17B10 | |
| SCHEMBL14412418 | 0.74 | ALDH1A1 (0.50) | KMT2AMEN1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2465850-A1 | THERAPEUTIC COMPOUNDS | Helicon Therapeutics, Inc. (US) | 2012-06-20 | — | — | EP | disclosed |
| WO-2007100851-A1 | THERAPEUTIC COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2007-09-07 | — | — | WO | disclosed |