Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966523 | 0.97 | IDO1 (0.36) | ALOX5APIDO1GSK3BDYRK1A | |
| SCHEMBL9966277 | 0.88 | ALOX5AP (0.38) | ALOX5AP | |
| SCHEMBL9966365 | 0.86 | USP2 (0.33) | IDO1 | |
| SCHEMBL9966514 | 0.85 | MAP4K4 (0.40) | — | |
| SCHEMBL9966413 | 0.82 | RIPK1 (0.37) | ALOX5APABL1 | |
| SCHEMBL9966449 | 0.82 | MAP4K4 (0.33) | — | |
| SCHEMBL9966486 | 0.81 | MAP4K4 (0.33) | — | |
| SCHEMBL9966391 | 0.80 | FFAR2 (0.33) | GSK3BDYRK1ALMNATLR7 | |
| SCHEMBL9966380 | 0.80 | PIK3CA (0.33) | — | |
| SCHEMBL9966408 | 0.78 | ALOX5AP (0.38) | ALOX5APIDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |