Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966565 | 0.92 | ALOX5AP (0.36) | MAP4K4ALDH1A1HDAC1LMNAALOX5AP | |
| SCHEMBL9966448 | 0.78 | MAP4K4 (0.35) | MAP4K4ALDH1A1HDAC1USP2TSHR | |
| SCHEMBL9966389 | 0.77 | ALOX5 (0.41) | MAP4K4ALDH1A1HDAC1ALOX5AP | |
| SCHEMBL9966408 | 0.77 | ALOX5AP (0.38) | MAP4K4ALDH1A1HDAC1LMNAALOX5AP | |
| SCHEMBL9966472 | 0.75 | IDO1 (0.40) | MAP4K4HDAC1ALOX5AP | |
| SCHEMBL9966296 | 0.75 | LMNA (0.53) | MAP4K4ALDH1A1HDAC1LMNATSHR | |
| SCHEMBL9966182 | 0.74 | IDO1 (0.42) | MAP4K4ALOX5AP | |
| SCHEMBL9966435 | 0.74 | LMNA (0.59) | MAP4K4ALDH1A1HDAC1LMNATSHR | |
| SCHEMBL9966467 | 0.74 | ALOX5AP (0.40) | MAP4K4ALOX5AP | |
| SCHEMBL9966577 | 0.73 | POLB (0.42) | MAP4K4ALDH1A1HDAC1LMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |