Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 8/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 7/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096010 | 0.86 | PEPD (0.41) | PEPDFKBP1AXPNPEP1 | |
| SCHEMBL16502012 | 0.85 | PEPD (0.40) | PEPDFKBP1AXPNPEP1 | |
| SCHEMBL8201750 | 0.80 | PEPD (0.42) | PEPDELANEFKBP1AXPNPEP1 | |
| SCHEMBL12599485 | 0.79 | CYP3A4 (0.49) | PEPDELANEXPNPEP1 | |
| SCHEMBL8246560 | 0.79 | FKBP1A (0.43) | PEPDFKBP1A | |
| SCHEMBL7316962 | 0.79 | CMA1 (0.51) | PEPDELANECMA1XPNPEP1 | |
| SCHEMBL8352620 | 0.79 | CMA1 (0.51) | PEPDELANECMA1XPNPEP1 | |
| SCHEMBL8168154 | 0.79 | CMA1 (0.51) | PEPDELANECMA1XPNPEP1 | |
| SCHEMBL15692923 | 0.76 | FKBP1A (0.46) | PEPDELANEFKBP1AXPNPEP1 | |
| SCHEMBL1985159 | 0.74 | ELANE (0.48) | ELANECMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082672-A2 | PROCESS AND INTERMEDIATES FOR PREPARING MACROLACTAMS | MERCK SHARP & DOHME CORP. (US) | 2012-06-21 | — | — | WO | disclosed |