SCHEMBL996689

SCHEMBL996689

CCc1cc(C(=O)O)c(C(=O)O)c(CC)c1CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 3/20 0.41
GABRD O14764 3/20 0.41
GABRA1 P14867 3/20 0.41
GABRB1 P18505 3/20 0.41
GABRG2 P18507 3/20 0.41
GABRB3 P28472 3/20 0.41
GABRA5 P31644 3/20 0.41
GABRA3 P34903 3/20 0.41
GABRA2 P47869 3/20 0.41
GABRB2 P47870 3/20 0.41
GABRA4 P48169 3/20 0.41
GABRE P78334 3/20 0.41
GABRA6 Q16445 3/20 0.41
GABRG1 Q8N1C3 3/20 0.41
GABRG3 Q99928 3/20 0.41
GABRQ Q9UN88 3/20 0.41
PTPN1 P18031 1/20 0.37
PTPN11 Q06124 1/20 0.37
KDM4E B2RXH2 2/20 0.34
CLCN2 P51788 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14989249 0.90 GABRP (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL28477751 0.86 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7920487 0.85 GABRP (0.40) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4626525 0.85 GABRP (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL3821056 0.85 GABRP (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL21948 0.84 KAT8 (0.46) PTPN1PPARG
SCHEMBL4639965 0.83 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10456941 0.83 PTPN1 (0.39) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29240829 0.83 GABRP (0.47) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11028104 0.83 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4385503-A2 ENTERIC COATING FOR SOFT CAPSULE Capsugel Belgium NV (BE) 2024-06-19 EP claimed
EP-2911654-B1 ENTERIC COATING FOR SOFT CAPSULE CAPSUGEL BELGIUM NV (BE) 2024-06-12 EP claimed
CN-116688214-A Medical gel with stable adhesion in moisture environment and preparation method thereof 北京福爱乐科技发展有限公司 2023-09-05 CN claimed
US-20230158004-A1 ENTERIC-COATED PREPARATION COMPRISING PIRFENIDONE HAVING IMPROVED SAFETY AND STABILITY, AND METHOD FOR PREPARING SAME YUNGJIN PHARM. CO., LTD. (KR) 2023-05-25 US claimed
CN-113476421-B Controlled release composition of febuxostat and preparation method thereof 江苏恒瑞医药股份有限公司 2023-04-07 CN claimed
CN-115531493-A Compound preparation and preparation method thereof 广西纯正堂制药有限公司 2022-12-30 CN claimed
CN-115381787-A New vitamin C enteric-coated pellet Yinqiao tablet and preparation method thereof 广西纯正堂制药有限公司 2022-11-25 CN claimed
CN-111405895-B Controlled release pharmaceutical composition and preparation method thereof 江苏恒瑞医药股份有限公司 2022-10-21 CN claimed
CN-113429662-B Bright color-changing sunshade net and preparation method thereof 绿地遮阳有限公司 2022-04-22 CN claimed
WO-2021215856-A1 ENTERIC-COATED PREPARATION COMPRISING PIRFENIDONE HAVING IMPROVED SAFETY AND STABILITY, AND METHOD FOR PREPARING SAME 영진약품 주식회사 (KR) 2021-10-28 WO claimed
CN-109985016-A A kind of controlled release composition of Febustat and preparation method thereof 江苏恒瑞医药股份有限公司 2019-07-09 CN claimed
CN-109078186-A A kind of stomach floating composition and preparation method thereof 江苏恒瑞医药股份有限公司 2018-12-25 CN claimed
US-20180056247-A1 PVDF POWDER FOR LIQUID SLURRIES ARKEMA INC (US) 2018-03-01 US claimed
EP-3268117-A1 PVDF POWDER FOR LIQUID SLURRIES Arkema, Inc. (US) 2018-01-17 EP claimed
CN-107427785-A PVDF powder for liquid slurry 阿科玛股份有限公司 2017-12-01 CN claimed
CN-107224431-A Improved release dosage form of Febustat and preparation method thereof 江苏恒瑞医药股份有限公司 2017-10-03 CN claimed
WO-2016144934-A1 PVDF POWDER FOR LIQUID SLURRIES ARKEMA INC. (US) 2016-09-15 WO claimed
CN-105566798-A Rigid carbon fiber composite material ANHUI RUIYAN NEW MAT TECH RES INST CO LTD 2016-05-11 CN claimed
US-5658558-A BLEND OF ACRYLIC HAIR FIXATIVE RESIN AND PLASTICIZER ROHM AND HAAS COMPANY (US) 1997-08-19 US claimed
EP-0705595-A2 Hair styling compositions ROHM AND HAAS COMPANY (US) 1996-04-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158004-A1 ENTERIC-COATED PREPARATION COMPRISING PIRFENIDONE HAVING IMPROVED SAFETY AND STABILITY, AND METHOD FOR PREPARING SAME SI, MLN, PIR GABRP 2991/4885GABRD 4691/4885GABRA1 4200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.