Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966793 | 0.97 | LTA4H (0.56) | LTA4HMEN1KMT2ADRD3HRH3 | |
| SCHEMBL9967005 | 0.95 | LTA4H (0.58) | LTA4HMEN1KMT2ADRD3HRH3 | |
| SCHEMBL9966961 | 0.92 | LTA4H (0.55) | LTA4HHRH3OPRK1ESR1ESR2 | |
| SCHEMBL9940088 | 0.91 | LTA4H (0.56) | LTA4HHRH3OPRK1ESR1ESR2 | |
| SCHEMBL9940306 | 0.91 | LTA4H (0.56) | LTA4HHRH3OPRK1ESR1ESR2 | |
| SCHEMBL9940186 | 0.89 | HRH3 (0.51) | LTA4HHRH3OPRK1 | |
| SCHEMBL9940254 | 0.89 | LTA4H (0.57) | LTA4HESRRGESR1ESR2NPC1 | |
| SCHEMBL9966735 | 0.89 | LTA4H (0.54) | LTA4HHRH3OPRK1ESR1ESR2 | |
| SCHEMBL9966789 | 0.88 | LTA4H (0.55) | LTA4HHRH3OPRK1ESR1ESR2 | |
| SCHEMBL9966732 | 0.88 | LTA4H (0.55) | LTA4HHRH3OPRK1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |