Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.51 |
| ▸ | LTA4H | P09960 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966786 | 0.97 | HRH3 (0.53) | HRH3LTA4HKDM4EOPRK1ALDH1A1 | |
| SCHEMBL9967004 | 0.95 | LTA4H (0.50) | HRH3LTA4HKDM4EOPRK1ALDH1A1 | |
| SCHEMBL9966973 | 0.89 | LTA4H (0.57) | HRH3LTA4HOPRK1 | |
| SCHEMBL9966961 | 0.89 | LTA4H (0.55) | HRH3LTA4HOPRK1 | |
| SCHEMBL9940306 | 0.88 | LTA4H (0.56) | HRH3LTA4HOPRK1 | |
| SCHEMBL9940088 | 0.88 | LTA4H (0.56) | HRH3LTA4HOPRK1 | |
| SCHEMBL9966995 | 0.88 | ESR1 (0.57) | HRH3LTA4HKDM4ESIGMAR1 | |
| SCHEMBL9940164 | 0.87 | KDM4E (0.52) | HRH3LTA4HKDM4EOPRK1ALDH1A1 | |
| SCHEMBL9966794 | 0.87 | KDM4E (0.48) | HRH3LTA4HKDM4EOPRK1ALDH1A1 | |
| SCHEMBL9966994 | 0.87 | KDM4E (0.48) | HRH3LTA4HKDM4EOPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |