SCHEMBL9968101

SCHEMBL9968101

Cn1c2ccc(C(C)(C)C)cc2c2ccncc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.44
ADORA2A P29274 1/20 0.44
HTR1D P28221 1/20 0.39
TOP2A P11388 1/20 0.38
ROCK2 O75116 3/20 0.38
KIF11 P52732 4/20 0.38
GABRA1 P14867 1/20 0.38
GABRA5 P31644 1/20 0.38
AAK1 Q2M2I8 1/20 0.37
NFATC1 O95644 1/20 0.37
GSK3B P49841 1/20 0.37
DYRK1A Q13627 1/20 0.37
NPY5R Q15761 1/20 0.36
PGR P06401 1/20 0.36
RORA P35398 1/20 0.36
RORC P51449 1/20 0.36
RORB Q92753 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968105 0.89 MAOA (0.43) ADORA3ADORA2AHTR1DTOP2AKIF11
SCHEMBL2604384 0.82 HTR1D (0.50) HTR1DKIF11NPY5RPGRRORA
SCHEMBL1609661 0.80 ADORA3 (0.54) ADORA3ADORA2ATOP2AROCK2NFATC1
SCHEMBL12464502 0.80 ADORA3 (0.50) ADORA3ADORA2ATOP2AROCK2AAK1
SCHEMBL9968122 0.79 KDM4E (0.41) ADORA3ADORA2ATOP2AROCK2AAK1
SCHEMBL29355852 0.79 ROCK2 (0.46) ADORA3ADORA2ATOP2AROCK2NFATC1
SCHEMBL2722137 0.79 ADORA3 (0.46) ADORA3ADORA2ATOP2AROCK2NFATC1
SCHEMBL16592460 0.79 ROCK2 (0.46) ADORA3ADORA2ATOP2AROCK2NFATC1
Benzene SCHEMBL28231296 0.79 HTR1D (0.47) HTR1DKIF11NPY5RPGRRORA
SCHEMBL12611168 0.79 HTR1D (0.47) HTR1DKIF11NPY5RPGRRORA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed