Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968107 | 0.80 | ADORA3 (0.41) | TOP2AADORA3ADORA2AMAPTHASPIN | |
| SCHEMBL9968155 | 0.80 | HPGD (0.40) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL9968103 | 0.78 | MAOA (0.43) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL9968112 | 0.78 | TOP2A (0.40) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL280029 | 0.76 | TOP2A (0.50) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL9968094 | 0.75 | AAK1 (0.30) | AAK1 | |
| SCHEMBL9968124 | 0.72 | TOP2A (0.40) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL9968110 | 0.71 | MAOA (0.39) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL9968105 | 0.71 | MAOA (0.43) | TOP2AMAOAMAOBACHECYP2D6 | |
| SCHEMBL18354602 | 0.71 | TOP2A (0.42) | TOP2AMAOAMAOBACHECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120153817-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |
| US-20120153817-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | FUJIFILM CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |