SCHEMBL280029

SCHEMBL280029

Cn1c2ccncc2c2cnccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.50
MAOA P21397 5/20 0.48
MAOB P27338 5/20 0.48
ACHE P22303 1/20 0.48
CYP2D6 P10635 1/20 0.45
GPR3 P46089 1/20 0.44
ATM Q13315 1/20 0.43
ADORA3 P0DMS8 1/20 0.42
ADORA2A P29274 1/20 0.42
NFATC1 O95644 1/20 0.41
GSK3B P49841 1/20 0.41
DYRK1A Q13627 1/20 0.41
CYP11B2 P19099 2/20 0.41
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
CASP1 P29466 1/20 0.38
RAB9A P51151 1/20 0.38
FGFR1 P11362 1/20 0.37
HASPIN Q8TF76 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2628358 0.91 ADORA3 (0.49) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL280028 0.89 GPR3 (0.64) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL29548306 0.89 GPR3 (0.64) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL18381763 0.88 MAOA (0.62) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL18381881 0.84 MAOA (0.58) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL18381814 0.84 MAOA (0.54) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL13100687 0.84 ACHE (0.49) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL13100686 0.83 TOP2A (0.47) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL8975963 0.83 MAOA (0.44) TOP2AMAOAMAOBACHECYP2D6
SCHEMBL22907184 0.82 TOP2A (0.42) TOP2AMAOAMAOBACHECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS UDC IRELAND LIMITED (IE) 2023-12-05 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 US disclosed
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20230225147-A1 ORGANIC LIGHT-EMITTING ELEMENT KYULUX, INC. (JP) 2023-07-13 US disclosed
US-20220153759-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 US disclosed
US-11335872-B2 Organic light-emitting device KYULUX, INC. (JP) 2022-05-17 US disclosed
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics UDC IRELAND LIMITED (IE) 2021-11-30 US disclosed
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
EP-1956011-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-08-13 EP disclosed
US-20080088230-A1 Organic electroluminescent element and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-04-17 US disclosed
US-20080088230-A1 Organic electroluminescent element and display KONICA MINOLTA HOLDINGS, INC. (JP) 2008-04-17 US disclosed
US-20080067925-A1 organic EL element showing high light emission efficiency and high color purity of the emission light, an organic EL element, a lighting device and a displaying device each using the metal complex is represented by the Formula 1 or isomer KONICA MINOLTA HOLDINGS, INC. (JP) 2008-03-20 US disclosed
US-20080067925-A1 organic EL element showing high light emission efficiency and high color purity of the emission light, an organic EL element, a lighting device and a displaying device each using the metal complex is represented by the Formula 1 or isomer KONICA MINOLTA HOLDINGS, INC. (JP) 2008-03-20 US disclosed
US-20080038586-A1 White Light Emitting Organic Electroluminescence Element, Display and Illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-14 US disclosed
US-20080038586-A1 White Light Emitting Organic Electroluminescence Element, Display and Illuminator KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-14 US disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070132372-A1 AMINE BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME KCNH2, SLC7A5, KCNH3 TOP2A 843/4885MAOA 42/4885MAOB 23/4885
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 TOP2A 2479/4885MAOA 588/4885MAOB 963/4885
US-20090017330-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME ICMT, ORAI2, ILK TOP2A 2078/4885MAOA 915/4885MAOB 1638/4885
US-11839140-B2 Metal complexes comprising diazabenzmidazolocarbene ligands and the use thereof in OLEDS OCIAD1, OCIAD2, DRD2 TOP2A 4574/4885MAOA 1877/4885MAOB 581/4885
US-20230286989-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 TOP2A 4642/4885MAOA 177/4885MAOB 120/4885
US-11189806-B2 Heteroleptic carbene complexes and the use thereof in organic electronics OCIAD2, OCIAD1, CLTB TOP2A 4578/4885MAOA 394/4885MAOB 108/4885
US-20220153759-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG TOP2A 4114/4885MAOA 589/4885MAOB 396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.