SCHEMBL9968166

SCHEMBL9968166

CC(C)(C)c1ccc2c(n1)c1ccccc1n2-c1cccc(-n2c3ccccc3c3nc(C(C)(C)C)ccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.40
KDM4E B2RXH2 3/20 0.40
ATM Q13315 1/20 0.40
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
NR1I2 O75469 1/20 0.35
AHR P35869 1/20 0.35
PTGER4 P35408 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 3/20 0.33
GAA P10253 1/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968184 0.93 L3MBTL1 (0.37) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968191 0.92 CCR1 (0.35) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968196 0.89 L3MBTL1 (0.34) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968231 0.89 L3MBTL1 (0.36) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968212 0.85 POLB (0.34) L3MBTL1KDM4EATMKMT2AMEN1
SCHEMBL9968186 0.81 PTGER4 (0.35) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968174 0.81 L3MBTL1 (0.38) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968148 0.80 KDM4E (0.38) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968138 0.79 MEN1 (0.40) L3MBTL1KDM4EATMKMT2AALDH1A1
SCHEMBL9968067 0.79 GPR3 (0.50) L3MBTL1KDM4EKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed