SCHEMBL9968231

SCHEMBL9968231

CC(C)(C)c1ccc2c(n1)c1ccccc1n2-c1cccc([Si](c2ccccc2)(c2ccccc2)c2cccc(-n3c4ccccc4c4nc(C(C)(C)C)ccc43)c2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
ALDH1A1 P00352 4/20 0.33
KMT2A Q03164 3/20 0.33
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
HPGD P15428 2/20 0.31
GAA P10253 2/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
MAPK1 P28482 2/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PDE7A Q13946 1/20 0.31
HSD17B10 Q99714 2/20 0.30
MEN1 O00255 2/20 0.30
LMNA P02545 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968166 0.89 L3MBTL1 (0.40) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL9968184 0.85 L3MBTL1 (0.37) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL9968191 0.82 CCR1 (0.35) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL5460427 0.79 L3MBTL1 (0.59) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL5465450 0.79 L3MBTL1 (0.59) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL5466449 0.79 L3MBTL1 (0.59) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL30414926 0.79 L3MBTL1 (0.59) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL23051438 0.79 KDM4E (0.45) L3MBTL1KDM4EATMALDH1A1HPGD
SCHEMBL9968196 0.79 L3MBTL1 (0.34) L3MBTL1KDM4EATMALDH1A1KMT2A
SCHEMBL9968212 0.78 POLB (0.34) L3MBTL1KDM4EATMKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed