SCHEMBL9968185

SCHEMBL9968185

CC(C)(C)Cc1ccc2c(n1)c1ccccc1n2-c1cccc(-c2cccc(-n3c4ccccc4c4nc(CC(C)(C)C)ccc43)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
PTGER4 P35408 2/20 0.33
PDE10A Q9Y233 1/20 0.32
CCR4 P51679 1/20 0.32
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
PDE7A Q13946 2/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 3/20 0.31
IL1R1 P14778 1/20 0.31
MEN1 O00255 2/20 0.30
GAA P10253 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
TLR7 Q9NYK1 1/20 0.30
PDE7B Q9NP56 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968189 0.93 PTGER4 (0.30) L3MBTL1KDM4EATMPTGER4
SCHEMBL9968187 0.93 ALDH1A1 (0.33) L3MBTL1KDM4EATMPTGER4PDE10A
SCHEMBL9968190 0.88
SCHEMBL9968242 0.86 KDM4E (0.34) L3MBTL1KDM4EATMPTGER4CCR4
SCHEMBL9968184 0.81 L3MBTL1 (0.37) L3MBTL1KDM4EATMPTGER4PDE10A
SCHEMBL9968186 0.80 PTGER4 (0.35) L3MBTL1KDM4EATMPTGER4PDE10A
SCHEMBL8739896 0.77 KDM4E (0.41) L3MBTL1KDM4EATMLMNAKMT2A
SCHEMBL8739893 0.77 KDM4E (0.41) L3MBTL1KDM4EATMLMNAKMT2A
SCHEMBL9968096 0.76 GPR3 (0.44) L3MBTL1KDM4EPTGER4LMNAKMT2A
SCHEMBL10090530 0.76 L3MBTL1 (0.39) L3MBTL1KDM4EATMPDE10AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed