SCHEMBL5460427

SCHEMBL5460427

c1ccc([Si](c2ccccc2)(c2cccc(-n3c4ccccc4c4ccccc43)c2)c2cccc(-n3c4ccccc4c4ccccc43)c2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.59
KDM4E B2RXH2 1/20 0.59
ATM Q13315 1/20 0.59
FOLH1 Q04609 1/20 0.36
ALDH1A1 P00352 3/20 0.35
PTPN1 P18031 1/20 0.35
KMT2A Q03164 3/20 0.34
MAPK8 P45983 2/20 0.34
TSHR P16473 1/20 0.34
IL1R1 P14778 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 2/20 0.33
MAPK9 P45984 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KDR P35968 1/20 0.33
GAA P10253 1/20 0.33
DUSP3 P51452 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5466449 1.00 L3MBTL1 (0.59) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL30414926 1.00 L3MBTL1 (0.59) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL5465450 1.00 L3MBTL1 (0.59) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL23622564 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL24985936 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL23622745 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL25449254 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL22907607 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL24089291 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1
SCHEMBL24064821 0.94 KDM4E (0.52) L3MBTL1KDM4EATMFOLH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12048238-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-23 US disclosed
US-12048238-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-23 US disclosed
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240237528-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-11 US disclosed
US-20240237528-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-11 US disclosed
US-20240215446-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215444-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215286-A1 LIGHT EMITTING DEVICE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215286-A1 LIGHT EMITTING DEVICE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-8871361-B2 Tetradentate platinum complexes UNIVERSAL DISPLAY CORPORATION (US) 2014-10-28 US disclosed
US-8748012-B2 Host materials for OLED UNIVERSAL DISPLAY CORPORATION (US) 2014-06-10 US disclosed
US-8748012-B2 Host materials for OLED UNIVERSAL DISPLAY CORPORATION (US) 2014-06-10 US disclosed
US-8409729-B2 Host materials for phosphorescent OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2013-04-02 US disclosed
US-8409729-B2 Host materials for phosphorescent OLEDs UNIVERSAL DISPLAY CORPORATION (US) 2013-04-02 US disclosed
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 US disclosed
US-20120298966-A1 Host materials for oled UNIVERSAL DISPLAY CORPORATION (US) 2012-11-29 US disclosed
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES UNIVERSAL DISPLAY CORPORATION (US) 2012-09-06 US disclosed
US-20070173657-A1 Tetraphenylsilane-carbazole compound, its preparation method and its use as host material for dopants of organic light emitting diode ACADEMIA SINICA (TW) 2007-07-26 US disclosed
US-20070173657-A1 Tetraphenylsilane-carbazole compound, its preparation method and its use as host material for dopants of organic light emitting diode ACADEMIA SINICA (TW) 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240215444-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME NFE2L2, SLC1A2, CRY1 L3MBTL1 2758/4885KDM4E 2828/4885ATM 4538/4885
US-20120298966-A1 Host materials for oled OCIAD2, OCIAD1, OSBP2 L3MBTL1 1065/4885KDM4E 3086/4885ATM 3251/4885
US-20240244952-A1 ORGANIC LIGHT-EMITTING DEVICE AND ORGANOMETALLIC COMPOUND LEF1, OCIAD1, OXA1L L3MBTL1 209/4885KDM4E 2066/4885ATM 3753/4885
US-20130026909-A1 HOST MATERIALS FOR PHOSPHORESCENT OLEDS OSBP2, OCIAD2, OCIAD1 L3MBTL1 1959/4885KDM4E 3835/4885ATM 3438/4885
US-12048238-B2 Organometallic compound and organic light-emitting device including the same TRPC1, PPOX, LAGE3 L3MBTL1 18/4885KDM4E 1546/4885ATM 2858/4885
US-20070173657-A1 Tetraphenylsilane-carbazole compound, its preparation method and its use as host material for dopants of organic light emitting diode DRD2, DRD3, DRD1 L3MBTL1 172/4885KDM4E 4575/4885ATM 1178/4885
US-20240215446-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME TPH1, HCRTR1, HTR3D L3MBTL1 954/4885KDM4E 1408/4885ATM 4188/4885
US-20120223634-A1 NOVEL TETRADENTATE PLATINUM COMPLEXES PDCD1LG2, TEC, TPR L3MBTL1 571/4885KDM4E 3818/4885ATM 2297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.