SCHEMBL9968537

SCHEMBL9968537

c1ccc(-c2cc(-c3cc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc(-n4c5ccccc5c5ccccc54)c3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.45
▸ MEN1 O00255 8/20 0.45
▸ MAPT P10636 8/20 0.45
▸ HPGD P15428 8/20 0.45
▸ ALDH1A1 P00352 7/20 0.45
▸ NTSR1 P30989 1/20 0.45
▸ KDM4E B2RXH2 6/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ ATM Q13315 1/20 0.45
▸ LMNA P02545 2/20 0.40
▸ GLA P06280 1/20 0.40
▸ ADORA2A P29274 1/20 0.40
▸ ADORA1 P30542 1/20 0.40
▸ HDAC4 P56524 1/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ MAOA P21397 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ PTK2B Q14289 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14426184 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL13100550 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL8400299 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL14425737 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL8400273 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL24725200 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL13100557 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL14425720 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL14425753 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1
SCHEMBL8400280 0.97 KMT2A (0.47) KMT2AMEN1MAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1718121-B1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO (JP) 2020-11-25 — — EP disclosed
US-10411192-B2 Aromatic amine compound, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2019-09-10 — — US disclosed
US-9966539-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2018-05-08 — — US disclosed
US-9966539-B2 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2018-05-08 — — US disclosed
US-9871203-B2 Aromatic amine derivative, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 — — US disclosed
US-9871203-B2 Aromatic amine derivative, organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2018-01-16 — — US disclosed
US-20160181526-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 — — US disclosed
US-20160181526-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 — — US disclosed
EP-3018119-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE Idemitsu Kosan Co., Ltd (JP) 2016-05-11 — — EP disclosed
US-20150287921-A1 AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2015-10-08 — — US disclosed
US-8105701-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 — — US disclosed
US-8105701-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2012-01-31 — — US disclosed
US-20110121277-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-05-26 — — US disclosed
US-20110121277-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-05-26 — — US disclosed
US-7906226-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2011-03-15 — — US disclosed
US-7906226-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2011-03-15 — — US disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 — — US disclosed
US-20070257600-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO., LTD. (JP) 2007-11-08 — — US disclosed
US-20070159083-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 — — US disclosed
US-20070159083-A1 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10411192-B2 Aromatic amine compound, organic electroluminescent element and electronic device AOC2, PNMT, TYR KMT2A 117/4885MEN1 2077/4885MAPT 153/4885
US-20160181526-A1 AROMATIC AMINE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE AOC2, PNMT, TYR KMT2A 117/4885MEN1 2077/4885MAPT 153/4885
US-20150287921-A1 AROMATIC AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE RER1, AFF1, ESR2 KMT2A 1402/4885MEN1 2658/4885MAPT 3884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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