Glycine

Glycine

SCHEMBL996872

NC(=O)O.NCC(=O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL30677914 1.00 OR51E2 (0.83)
Glycine SCHEMBL10883072 0.96 OR51E2 (0.77)
Glycine SCHEMBL10883045 0.96 OR51E2 (0.77)
Glycine SCHEMBL11272876 0.96 OR51E2 (0.77)
Glycine SCHEMBL29248317 0.92 OR51E2 (0.83)
Glycine SCHEMBL13739339 0.92
Glycine SCHEMBL3640989 0.91 GLRA1 (1.00)
Glycine SCHEMBL93765 0.91 GLRA1 (1.00)
Glycine SCHEMBL391786 0.91 GLRA1 (1.00)
Glycine SCHEMBL2116443 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727600-B1 AMINO ACID CARBAMATE COMPLEXES COLGATE PALMOLIVE CO (US) 2023-09-20 EP claimed
US-10857083-B2 Amino acid carbamate complexes COLGATE-PALMOLIVE COMPANY (US) 2020-12-08 US claimed
EP-3727600-A1 AMINO ACID CARBAMATE COMPLEXES Colgate-Palmolive Company (US) 2020-10-28 EP claimed
CN-111479614-A Amino acid carbamate complexes 高露洁-棕榄公司 2020-07-31 CN claimed
EP-3529369-A1 BINDING COMPOUND AND USES THEREOF The Queen's University of Belfast (GB) 2019-08-28 EP claimed
US-20190183765-A1 Amino Acid Carbamate Complexes COLGATE-PALMOLIVE COMPANY (US) 2019-06-20 US claimed
WO-2018078351-A1 BINDING COMPOUND AND USES THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-05-03 WO claimed
US-20090192095-A1 AMINO ACID AND PEPTIDE PRODRUGS OF OPIOID ANALGESICS WITH REDUCED GI SIDE-EFFECTS SHIRE LLC (US) 2009-07-30 US claimed
WO-2009092073-A2 AMINO ACID AND PEPTIDE PRODRUGS OF OPIOID ANALGESICS WITH REDUCED GI SIDE-EFFECTS SHIRE LLC (US) 2009-07-23 WO claimed
WO-2009092071-A2 AMINO ACID AND PEPTIDE PRO-DRUGS OF PHENOLIC ANALGESICS AND USES THEREOF SHIRE LLC (US) 2009-07-23 WO claimed
US-20090186832-A1 AMINO ACID PEPTIDE PRO-DRUGS OF PHENOLIC ANALGESICS AND USES THEREOF SHIRE LLC (US) 2009-07-23 US claimed
EP-0835659-B1 Use of non-peptidic bradykinin antagonists in the preparation of medicaments for the treatment and prevention of Alzheimer's disease AVENTIS PHARMA GMBH (DE) 2004-12-15 EP claimed
CN-1433459-A Process of preparing detergent bar composition UNILEVER NV (NL) 2003-07-30 CN claimed
US-5952346-A INHIBITS THE ACTIONS OF THE ALZHEIMER'S PROTEIN AMYLOID (BETA/A4) IN ISOLATED ENDOTHELIAL CELLS; QUINOLINE DERIVATIVES HOECHST MARION ROUSSEL DEUTSCHLAND GMBH (DE) 1999-09-14 US claimed
US-20260027047-A1 HYDROGELS FOR CELL THERAPY ADOCIA (FR) 2026-01-29 US disclosed
EP-4588488-A1 HYDROGELS FOR CELL THERAPY Adocia (FR) 2025-07-23 EP disclosed
EP-4554983-A1 HYDROGELS FOR CELL THERAPY Adocia (FR) 2025-05-21 EP disclosed
EP-0112580-A1 Process for preparing phosphonomethylated amino acids STAUFFER CHEMICAL COMPANY (US) 1984-07-04 EP disclosed
US-4439373-A Process for preparing phosphonomethylated amino acids STAUFFER CHEMICAL COMPANY (US) 1984-03-27 US disclosed
US-4434144-A ACYCLIC AMINE, AS2O3 OR AMONIA AND CARBONATE GIAMMARCO GIUSEPPE (IT) 1984-02-28 US disclosed