Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16530080 | 0.94 | ALDH1A1 (0.50) | POLBKMT2ACYP2D6ALDH1A1PKM | |
| SCHEMBL9936986 | 0.91 | POLB (0.38) | POLBKMT2ACYP2D6MEN1TDP1 | |
| SCHEMBL9969257 | 0.88 | PTGS2 (0.36) | POLBALDH1A1PKMMMEGAA | |
| SCHEMBL16529951 | 0.87 | MME (0.56) | KMT2AMEN1MMEHDAC3HDAC4 | |
| SCHEMBL9936577 | 0.87 | ALDH1A1 (0.46) | POLBALDH1A1PKMMMEGAA | |
| SCHEMBL15328999 | 0.86 | MME (0.46) | KMT2AMEN1TDP1MMEGAA | |
| SCHEMBL9937430 | 0.86 | MME (0.43) | KMT2AMEN1ALDH1A1MMEL3MBTL1 | |
| SCHEMBL9937977 | 0.84 | MME (0.50) | MMEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16529879 | 0.84 | MEN1 (0.45) | KMT2AMEN1MMEL3MBTL1TSHR | |
| SCHEMBL9969500 | 0.84 | HDAC3 (0.40) | POLBKMT2AMEN1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | claimed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | claimed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | claimed |
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| WO-2012079938-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | KRT18, KLHL20, IK | POLB 1763/4885KMT2A 144/4885CYP2D6 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.