Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968852 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MCOLN3TYRESR1CA3 | |
| SCHEMBL9969787 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MCOLN3TYRESR1CA3 | |
| SCHEMBL15341222 | 0.86 | ALDH1A1 (0.35) | ALDH1A1MCOLN3 | |
| SCHEMBL9937017 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MCOLN3TYRESR1ESR2 | |
| SCHEMBL9937375 | 0.81 | TYR (0.41) | TYRCA3 | |
| SCHEMBL9938037 | 0.80 | TYR (0.40) | TYRCA3 | |
| SCHEMBL9968851 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TYRCA3 | |
| SCHEMBL15341257 | 0.80 | TYR (0.40) | ALDH1A1TYRCA3 | |
| SCHEMBL9968948 | 0.80 | TYR (0.40) | TYRCA3 | |
| SCHEMBL9937617 | 0.78 | L3MBTL1 (0.49) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | claimed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | claimed |
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| WO-2012079938-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | KRT18, KLHL20, IK | ALDH1A1 222/4885MCOLN3 451/4885TYR 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.