Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507186 | 1.00 | GAA (0.47) | GAARAB9APTGS2ALDH1A1KDM4E | |
| SCHEMBL9936974 | 0.81 | GAA (0.45) | GAAALDH1A1KDM4EMAPT | |
| SCHEMBL9936971 | 0.81 | GAA (0.45) | GAAALDH1A1KDM4EMAPT | |
| SCHEMBL3927028 | 0.78 | CTSL (0.71) | GAARAB9AALDH1A1CTSLTP53 | |
| SCHEMBL28790851 | 0.78 | CTSL (0.71) | GAARAB9AALDH1A1CTSLTP53 | |
| SCHEMBL12149993 | 0.76 | POLB (0.63) | GAARAB9AALDH1A1CTSLTP53 | |
| SCHEMBL3927052 | 0.75 | TSHR (0.52) | GAARAB9AALDH1A1KDM4EPKM | |
| SCHEMBL13320482 | 0.75 | KLKB1 (0.52) | GAARAB9ATP53 | |
| SCHEMBL13352182 | 0.75 | KLKB1 (0.52) | GAARAB9ATP53 | |
| SCHEMBL242242 | 0.75 | TACR1 (0.71) | GAARAB9AALDH1A1TP53TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651897-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2020-04-01 | — | — | EP | claimed |
| US-20210401709-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'ORÉAL (FR) | 2021-12-30 | — | — | US | disclosed |
| US-11052028-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2021-07-06 | — | — | US | disclosed |
| EP-2651897-B1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | OREAL (FR) | 2020-04-01 | — | — | EP | disclosed |
| US-20160045420-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2016-02-18 | — | — | US | disclosed |
| US-20160045420-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2016-02-18 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| US-9138392-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | L'OREAL (FR) | 2015-09-22 | — | — | US | disclosed |
| WO-2012080075-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045420-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | CBR3, RTN3, HRH4 | GAA 4768/4885RAB9A 4095/4885PTGS2 2848/4885 |
| US-20210401709-A1 | PROCESS FOR DEPIGMENTING KERATIN MATERIALS USING THIOPYRIDINONE COMPOUNDS | CBR3, HRH4, RTN3 | GAA 4751/4885RAB9A 3925/4885PTGS2 2511/4885 |
| US-11052028-B2 | Process for depigmenting keratin materials using thiopyridinone compounds | KRT18, PKN1, PTMA | GAA 2542/4885RAB9A 3028/4885PTGS2 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.