Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9964983 | 0.88 | LMNA (0.43) | HTR7HTTLMNAP2RY12SMN1; SMN2 | |
| SCHEMBL9938294 | 0.78 | NOS3 (0.42) | P2RY12SMN1; SMN2TDP1KDM4EKMT2A | |
| SCHEMBL18975382 | 0.77 | KDM4E (0.43) | SMN1; SMN2TDP1KDM4EHTR1AKMT2A | |
| SCHEMBL9964989 | 0.77 | SMN1; SMN2 (0.47) | HTTSMN1; SMN2TDP1KDM4EKMT2A | |
| SCHEMBL9964980 | 0.76 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2TDP1KDM4EKMT2A | |
| SCHEMBL9964981 | 0.74 | POLB (0.48) | P2RY12SMN1; SMN2POLB | |
| SCHEMBL9970829 | 0.72 | KDM4E (0.46) | HTR7SMN1; SMN2KDM4EKMT2APOLB | |
| SCHEMBL9964962 | 0.70 | KDM4E (0.45) | HTTKDM4EKMT2APOLBMEN1 | |
| SCHEMBL9965014 | 0.67 | SMN1; SMN2 (0.37) | HTTSMN1; SMN2TDP1KDM4EKMT2A | |
| SCHEMBL9965008 | 0.67 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2TDP1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080321-A2 | DYE COMPOSITION COMPRISING A HETEROCYCLIC OXIDATION BASE AND A 4-AMINOINDOLE COUPLER | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |