Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14346016 | 1.00 | ACHE (1.00) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL11513729 | 0.77 | ACHE (0.62) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL585584 | 0.77 | ACHE (0.61) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL586791 | 0.77 | ACHE (0.61) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL575222 | 0.74 | ACHE (0.58) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL1091759 | 0.73 | ACHE (0.57) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL12305471 | 0.73 | ACHE (0.57) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL93674 | 0.73 | ACHE (0.57) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL575308 | 0.71 | ACHE (0.55) | ACHENPSR1MEN1KMT2AGAA | |
| SCHEMBL575198 | 0.71 | ACHE (0.55) | ACHENPSR1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349538-A1 | Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation | Human BioMolecular Research Foundation (US) | 2017-12-07 | — | — | US | disclosed |
| US-20170349538-A1 | Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation | Human BioMolecular Research Foundation (US) | 2017-12-07 | — | — | US | disclosed |
| US-9751831-B2 | Blood brain barrier-penetrating oximes for cholistenerases reactivation | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2017-09-05 | — | — | US | disclosed |
| US-9751831-B2 | Blood brain barrier-penetrating oximes for cholistenerases reactivation | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2017-09-05 | — | — | US | disclosed |
| US-20140051712-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2014-02-20 | — | — | US | disclosed |
| US-20140051712-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2014-02-20 | — | — | US | disclosed |
| WO-2012083261-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20070286846-A1 | Novel methods for ester detoxication | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140051712-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | BCHE, ACHE, PYGB | ACHE 2/4885NPSR1 1532/4885MEN1 3539/4885 |
| US-20070286846-A1 | Novel methods for ester detoxication | CES2, BCHE, ACHE | ACHE 3/4885NPSR1 2475/4885MEN1 4804/4885 |
| US-20170349538-A1 | Blood Brain Barrier-Penetrating Oximes for Cholinesterase Reactivation | ACHE, BCHE, PYGB | ACHE 1/4885NPSR1 1357/4885MEN1 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.