Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310223 | 0.80 | TSHR (0.34) | ALDH1A1NOS3NOS1NOS2ESR2 | |
| SCHEMBL16864083 | 0.74 | — | — | |
| SCHEMBL2377735 | 0.72 | MAOA (0.32) | KDM4EALDH1A1MAPTHPGDALOX15 | |
| SCHEMBL7312356 | 0.71 | ESR2 (0.36) | KDM4EALDH1A1MAPTESR2 | |
| SCHEMBL14854669 | 0.70 | MAOA (0.34) | KDM4E | |
| SCHEMBL14855399 | 0.70 | KDM4E (0.38) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL8743950 | 0.69 | — | — | |
| SCHEMBL4733343 | 0.66 | — | — | |
| SCHEMBL14854783 | 0.65 | SMN1; SMN2 (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL23680212 | 0.65 | TGM2 (0.50) | ALDH1A1MAPTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |