Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9612244 | 0.95 | KMT2A (0.47) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17586498 | 0.93 | KMT2A (0.44) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16356426 | 0.89 | GAA (0.46) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16526510 | 0.88 | KMT2A (0.42) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL17029296 | 0.88 | KMT2A (0.42) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9612258 | 0.82 | AKT1 (0.43) | KMT2AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15290261 | 0.81 | HDAC1 (0.48) | KMT2AALDH1A1CYP2D6ACHE | |
| SCHEMBL15362875 | 0.79 | ALDH1A1 (0.44) | KMT2AGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1064815 | 0.79 | ALDH1A1 (0.44) | KMT2AGAASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22421442 | 0.78 | KMT2A (0.43) | KMT2AGAASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202509-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |